About 70 hospital hubs in the UK are gearing up to give the Pfizer/BioNTech jab to over-80s and some health and care staff, after regulators approved the vaccine's use last week.

Margaret Keenan, who turns 91 next week, said it was the "best early birthday present" to receive the jab as the UK begins the biggest vaccination programme in NHS history.

Trials are being planned in the UK to see if combining Covid vaccines might give the best protection.

American regulators are yet to approve the vaccine, despite the UK pushing ahead with mass rollout.

The peer-reviewed work in the Lancet medical journal confirms the vaccine is 'safe and protects'.